Buruli ulcer (Epidemiology, Transmission, Disease Management)
The transmission routes of Mycobacterium ulcerans from aquatic habitats to humans and other small mammals remain unknown. The bacterium however continues to cause debilitating skin infections (Buruli ulcer) in many rural population in the tropical regions of the globe. The need to put in preventive measures and early management of human infection has been prioritized by the WHO and the control programmes of endemic. Our research has focused on elucidating the modes of transmission of Buruli ulcer and other non-tuberculous infections, and the design and implementation of innovative interventions for skin NTD management.
- Determine ecological factors influencing the transmission and virulence of aquatic non-tuberculous mycobacteria (NTM).
- Elucidating the transmission of Buruli ulcer from aquatic environments to humans and other small mammals.
- Development of mobile based applications for skin disease diagnosis, treatment, and management in deprived communities
- Tracking human Buruli ulcer infections from community-associated and used aquatic environments.
- Gyamfi, E., Narh, CA., Quaye, C. et al. Microbiology of secondary infections in Buruli ulcer lesions; implications for therapeutic interventions. BMC Microbiol 21, 4 (2021). https://doi.org/10.1186/s12866-020-02070-5
- Narh CA, Mosi L, Quaye C, Dassi C, Konan DO, Tay SCK, de Souza DK, Boakye DA, Bonfoh B (2015) Source Tracking Mycobacterium ulcerans Infections in the Ashanti Region, Ghana. PLoS Neglected Tropical Diseases 9(1): e0003437.doi:10.1371/journal.pntd.0003437
- de Souza DK, Quaye C, Mosi L, Addo P, Boakye DA. (2012). A quick and cost-effective method for the diagnosis of Mycobacterium ulcerans infection. BMC infectious diseases.;12:8.
More publications can be found at:
PubMed Bibliography: https://www.ncbi.nlm.nih.gov/myncbi/charles.quaye.2/bibliography/public/