Findings from the multi-target antimalarial from medicinal plants research group (MAPReG) project titled “Developing an alternate anti-malarial from medicinal plants: Exemplifying the multi-target concept in malaria drug discovery,” include the ff:

• Strong anti-malarial activity as deduced from the IC₅₀ values <20 µg/ml has been observed for 9 out of 27 fractions from the Carapa procera,  Alchornea cordifolia and Milletia zechiana
• Acute and sub-acute toxicity assessment so far done for two of the fractions shows a good safety profile.
• Demonstration that fractions of Carapa procera and Alchornea cordifolia may be safe immunomodulators that can treat malaria